Publications

Alsayegh, K.A., Sheridan, S., Iyer, S., and R. R. Rao. 2018. Knockdown of CDK2AP1 in Human Embryonic Stem Cells reduces the threshold for differentiation. PLoS One 13(5): e0196817.

Tompkins, E., Faris, S., Hughes, L., Maurakis, E., Lesnefsky, E.J., Rao, R.R., and S. Iyer. 2017. Arts, Science, Engineering and Medicine Collaborate to Educate Public on Bioenergetics. Research Reports. [S.l.], v. 1, n. 1.

Sarkar S, Konar S, Puvvada N, Rajput S, Kumar BP, Rao RR, Pathak A, Fisher PB, Mandal M. 2017. Micellear Gold nanoparticle as delivery vehicle for dual tyrosine kinase inhibitor ZD6474 for metastatic breast cancer treatment. Langmuir. Jul 12. doi: 10.1021/acs.langmuir.7b01072.

Swaminathan G, Gadepalli V, Stoilov, I., Mecham, R.P., Rao R.R., and Ramamurthi A. 2017. Pro-elastogenic effects of bone marrow mesenchymal stem cell-derived smooth muscle cells on cultured aneurysmal smooth muscle cells. J Tissue Eng Regen Med. 11(3):679-693

Bano, S., S. Kundu and Rao, R.R.*. 2015. Silk 3D matrices incorporated human neural progenitor cells for neural tissue engineering applications.  Polymer Journal. Advance Online Publication (2 September).

Puvvada, N., Rajput, S., Prashanth Kumar, B.N., Sarkar, S., Konar, S., Brunt, K.R., Rao, R.R., Mazumdar, A., Das, S.K., Basu, R., Fisher, P.B., Mandal, M.M., and A. Pathak. 2015. Novel ZnO hollow-nanocarriers containing paclitaxel targeting folate-receptors in a malignant pH-microenvironment for effective monitoring and promoting breast tumor regression. Scientific Reports. 5, Article number: 11760.

Rao, R.R* and S. Iyer. 2015. Stem cells, neural progenitors, and engineered stem cells. Methods in Molecular Biology- Neuronal Cell Death. 1254:255-67.

Mallepally, R.R., Marin, M.A., Surampudi, V., Banu, S., Rao, R.R., Kundu, S.C and M.A. McHugh. 2015. Silk Fibroin Aerogels: Potential Scaffolds for Tissue Engineering Applications. Biomedical Materials. 10(3):035002.

Alsayegh, K., Gadepalli, V.S., Iyer, S., and R.R. Rao*. 2015. Knockdown of CDK2AP1 in Human Dermal Fibroblasts induces p53-Dependent Senescence. PLoS One. 10(3):e0120782.

Prashanth, B.N., Rajput, S., Sarkar, S., Das, S., Emdad, L., Sarkar, D., Venkatesan, P., Dey, G., Konar, S., Brunt, K., Rao, R.R., Mazumdar, A., Kundu, S., Mahanty, A., Fisher, P.B., and M. Mandal. 2015. Sequential release of drugs from Hollow Manganese Ferrate nanocarriers for Breast cancer therapy. Journal of Materials Chemistry B: 3, 90-101.

Gadepalli, V., Deb, S.P., Deb, S and R.R. Rao*. 2014. Lung Cancer Stem cells, p53 mutations and MDM2. In “Mutant p53 and MDM2 in Cancer”. Subcell Biochem. 2014;85:359-70.

Moustafa, M.E., Gadepalli, V.S., Elmak, A.A., Lee, W., Rao, R.R.*, and V.K. Yadavalli*. 2014. Large area micropatterning of cells on polydimethylsiloxane surfaces. J Biological Engineering. 8(1):24.

King, A., Chakrabarty, S., Zhang, W., Zeng, X., Wood, L., Ohman, D.E., Abraham, S., Rao., R.R., and K.J. Wynne. 2014. High antimicrobial effectiveness with low hemolytic and cytotoxic activity for PEG/quaternary copolyoxetanes and a geometric model for polycation – bacterial membrane interactions. Biomacromolecules. 15(2):456-67.

Gadepalli, V., Vaughn, C., and R.R. Rao*. 2013. Isolation and characterization of murine multipotent lung stem cells. Methods in Molecular Biology- p53 Protocols, Second Edition”. 962:183-191.

Eroshenko,N., Ramachandran, R., Yadavalli, V.K., and R.R.Rao*. 2013. Effect of substrate stiffness on early human embryonic stem cell differentiation. Journal of Biological Engineering. 7(1):7.

Bashur, C., Rao, R.R*. and A. Ramamurthi. 2013. Perspectives on Stem Cell-Based Elastic Matrix Regenerative Therapies for Abdominal Aortic Aneurysms. Stem Cells Translational Medicine. 2(6): 401-408.

Shirley, M.L., Johnson, A.V., Rao, R.R., Boyd,N.L., Stice, S.L., Puett.D., and P. Narayan. 2012. Bone morphogenetic protein-4 affects both trophoblast and non-trophoblast lineage-associated gene expression in human embryonic stem cells. Stem Cell Discovery. 2(4):163-175.

Sachs PC, Francis MP, Zhao M, Brumelle J, Rao RR, Elmore LW, Holt SE. 2012. Defining essential stem cell characteristics in adipose-derived stromal cells extracted from distinct anatomical sites. Cell and Tissue Research. 349(2): 505-515. May 25. [Epub ahead of print]

Sheridan, S.D., Surampudi, V., and R.R.Rao*. 2012. Analysis of Embryoid Bodies Derived from Human Induced Pluripotent Stem Cells as a Means to Assess Pluripotency. Stem Cells International. 738910. Epub 2012 Mar 1.

Iyer, S., Bergquist, K.E., Young, K., Gnaiger, E., Rao, R.R., and J.P. Bennett. Jr. 2012. Mitochondrial gene therapy improves respiration, biogenesis and transcription in G11778A Leber’s hereditary optic neuropathy and T8993G Leigh’s syndrome cells. Human Gene Therapy. 23(6):647-57. Apr 17. [Epub ahead of print].

Vanee N., Roberts S.B., Riggs, M.J. Rao R.R.*, and Fong, S.S*. 2012. Identification of Metabolic Changes in Genetically Unstable Stem Cells Using Model Analysis of Gene Expression. Chemistry and Biodiversity. 9(5):911-29.

Iyer, S., Xiao, E., Alsayegh, K., Riggs, M.J., Eroshenko, N., Bennett. J.P., and R.R. Rao*. 2012. Mitochondrial Gene Replacement in human pluripotent stem cell derived neural progenitors. Gene Therapy. 19(5):469-75. Sep 15. 2011. Epub Ahead of print.

Dodla, M., Young, A., Johnson, A.V., Hasneen, K., Rao, R.R., Machacek, D., and S.L. Stice. 2011. Differing Lectin Binding Profiles among Human Embryonic Stem Cells and Derivatives Aid in the Isolation of Neural Progenitor Cells. PLoS ONE 6(8): e23266.

Chakrabarty, S., King, A., Kurt, P., Zhang, W., Ohman, D., Wood, L., Lovelace, C., Rao, R.R., and K.J. Wynne. 2011. Highly Effective, Water Soluble, Hemocompatible 1,3-Propylene Oxide-Based Antimicrobials: Poly[(3,3-Quaternary/PEG)-Copolyoxetanes]. Biomacromolecules. 12(3):757-69.

Abraham, S., Riggs, M.J.. Xiao, E., Gadepalli, V., Alsayegh, K, and R.R.Rao*. 2011. Generation, characterization and propagation of human induced pluripotent stem cells. In “Stem Cells – From Mechanisms to Technologies”. World Scientific Publishing and Imperial College Press.

Abraham, S., Riggs, M.J., Nelson, K., Lee, V., and R.R. Rao*. 2010. Characterization and application of human fibroblast-derived extracellular matrix for human pluripotent stem cell propagation. Acta Biomaterialia. 6(12): 4622-4633.

Abraham, S., Sheridan, S.D., Miller, B., and R. R. Rao*. 2010. Stable propagation of human embryonic and induced pluripotent stem cells on decellularized human substrates. Biotechnology Progress. 26(4): 1126-1134.

Rao, R.R.*, Dhara, S.D., Iyer, S., and D. Machacek. 2010. Flow cytometric characterization of neural progenitors derived from human pluripotent stem cells. In “Flow Cytometric Applications in Stem Cell Research and Tissue Regeneration”. Wiley Publishers: 211-222

Pascual, E.Y., Riggs, M.J., and R.R.Rao*. 2010. Immunocytochemical analysis of human pluripotent stem cells using a self-made cytospin apparatus. Journal of Visualized Experiments. 38, doi: 10.3791/1944.

Abraham, S, Sheridan, S.D., Laurent, L.C., Albert, K., Stubban, C., Ulitsky, I., Miller, B., Loring, J.F., and R. R. Rao*. 2010. Propagation of human embryonic and induced pluripotent stem cells in an indirect co-culture system. Biochemical and Biophysical Research Communications. 393(2): 211-216.

West, F.D., Roche-Rios, M.I., Abraham, S., Rao, R.R., Natrajan, M.S., and S. L. Stice. 2010. KIT Ligand and Bone Morphogenetic Protein 1 Signaling Enhances Human Embryonic Stem Cell to Germ-Like Cell Differentiation. Human Reproduction. Jan;25(1):168-178. Epub 2009 Oct 19.

Adams, B.R., Golding, S.E., Rao, R.R., and K. Valerie. 2010. Dynamic dependence of ATR and ATM in DNA double-strand break repair in human embryonic stem cells and differentiated neural progenies. PLoS ONE 5(4): e10001.

Iyer, S., Alsayegh, K., Abraham, S., and R.R. Rao*. 2009. Stem cell based models and therapies for neurodegenerative diseases. Critical Reviews in Biomedical Engineering. 37(4): 321-353.

Wilczynska, K.M., Singh, S.K., Adams, B., Bryan, L.E, Rao, R.R, Valerie, K., Wright, S., Griswold-Prenner I., and T. Kordula. 2009. Nuclear Factor I isoforms regulate gene expression during the differentiation of human neural progenitors to astrocytes. Stem Cells. 27(5):1173-1181.

Abraham, S., Eroshenko, N., and R. R. Rao*. 2009. Role of bio-inspired polymers in determination of pluripotent stem cell fate. Regenerative Medicine. 4(4): 561-578.

Dhara, S.K., Hasneen, K., Machacek, D.W., Boyd, N.L., Rao, R.R., and S.L. Stice. 2008. Human neural progenitor cells derived from embryonic stem cells in feeder-free cultures. Differentiation. 76(5): 454-464.

Boyd, N.L., Dhara, S.K., Rekaya, R., Godbey, E.A., Hasneen, K., Rao, R.R., West III, F.D., Gerwe, B.A., and S.L. Stice. 2007. Bone Morphogenic Protein 4 Promotes Development and Outgrowth of Primitive Vascular Networks in Human Embryonic Stem Cell Derived Embryoid Bodies. Experimental Biology and Medicine. 232: 833-843

Rao, R.R.*, Johnson, A.V., and Stice, S.L. 2007. Cell surface markers in human embryonic stem cells. Methods in Molecular Biology-Stem Cell Assays. 407: 51-61.

Tibbitts, D., Rao, R.R., Shin, S., West, F., and Stice, S.L. 2006. Uniform populations of adherent neural progenitor cells derived from rhesus monkey embryonic stem cells. Stem Cells and Development. 15(2): 200-208.

Shin, S., Mitalipova, M., Noggle, S., Tibbitts, D., Venable, A., Rao, R.R., and S.L. Stice. 2006. Long term proliferation of human embryonic stem cell-derived neuroepithelial cells using defined adherent culture conditions. Stem Cells. 24(1): 125-138.

Rao, R.R., Mitalipova, M.M., Hoyer, D., Jones, K., Johnson, J., Dalton, S., Meisner, L., and S.L. Stice. 2005. Preserving the genetic integrity of human embryonic stem cell lines. Nature Biotechnology. 23(1): 19-20.

Rao, R. R., and S.L. Stice. 2004. Gene Expression Profiling of Embryonic Stem Cells Leads to Greater Understanding of Pluripotency and Early Developmental Events. Biology of Reproduction. 71(6):1772-1778.

Rao, R.R., Calhoun, J., Qin, X., Rekaya, R., Clark, J., and S.L. Stice. 2004. Comparative transcriptional profiling of two human embryonic stem cell lines. Biotechnology and Bioengineering. Oct 18;88(3):273-286.

Rao, R.R., Calhoun, J., Warrenfeltz, S., Rekaya, R., Dalton, S., McDonald, J., and S.L. Stice. 2004. Transcriptional profiling of initial differentiation events in human embryonic stem cells. Biochemical and Biophysical Research Communications 323(2):453-464.

Rao, R.R. and W.S. Kisaalita. 2004. A single magnetic field exposure system for sequential investigation of real-time and downstream cellular responses. Bioelectromagnetics, 25(1):27-32.

McCloskey, K. Lyons, I., Rao, R.R., Stice, S.L., and R.M. Nerem. 2003. Purified and proliferating endothelial cells derived and expanded in vitro from embryonic stem cells. Endothelium, 10(6):329-336.

Rao, R.R. and W.S. Kisaalita. 2002. Biochemical and electrophysiological differentiation profile of a human neuroblastoma (IMR-32) cell line. In Vitro-Cell Dev Biol Anim,38(8):450-456.

Rao, R.R. Halper, J., and W.S. Kisaalita. 2002. Effects of 60 Hz electromagnetic field exposure on APP695 transcription in differentiating human neuroblastoma cells. Bioelectrochemistry, 57:9-15.